- A Case of Rheumatoid Leptomeningitis
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Young-Do Kim, Sung-Woo Chung, Kwang-Soo Lee
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Published online June 30, 2013
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- A Case of Rheumatoid Leptomeningitis
- 한국인구집단에서 체질량지수와 편두통: Korean Headache Survey 자료 분석
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Soo Hwan Yim, Byung-Kun Kim, Kwang-Soo Lee, Kyungmi Oh, Min Kyung Chu
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Korean J Headache. 2012;13(1):7-12. Published online June 30, 2012
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- Objective: Obesity and underweight are known to be exacerbating factors for migraine in Western countries. In Asian countries including Korea, migraine prevalence and body mass index (BMI) are often lower than Western countries. To investigate the relationship of BMI to the prevalence, frequency, duration and severity of migraine in Korea.
Methods
We selected a stratified random population sample of Koreans over age 18 and evaluated them with a 12-item semi-structured interview designed to identify headache type using ICHD-2 criteria. The participants were divided into 4 categories based on the World Health Organization BMI categories for Asian populations: underweight (<18.5), normal weight (18.5-22.9), overweight (23.0-24.9) and obese (≥25.0).
Results
Of 1,507 participants, 71 were underweight (4.8%), 768 had a normal BMI (51.3%), 326 were overweight (21.8%) and 330 were obese (22.1%). Prevalence varied by headache type for migraine (6.0%) and PM (11.5%). Migraine, prevalence did not vary with BMI, but migraine attack frequency per month was higher both in the underweight (8.6±9.1) and the obese groups (7.3±11.2) in comparison with the normal weighted (2.5±2.7). Duration of headache attack and pain intensity (VAS score) were not significantly different between these groups.
Conclusions
In Koreans, obesity and underweight are associated with migraine attack frequency.
- 한국인구집단에서 편두통환자의 냄새공포증과 편두통 대체진단기준의 타당도 평가
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Yeo Jin Kim, Soo-Jin Cho, Byung-Kun Kim, Kwang-Soo Lee, Byung-Chul Lee, Min Kyung Chu
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Korean J Headache. 2011;12(2):91-96. Published online December 31, 2011
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- Objective: Osmophobia, intolerance to smell, is often reported by migraine patients during headache attack and is included as an item of alternative diagnostic criteria for migraine in the appendix of ICHD-2. Most of previous reports on osmo- phobia were hospital-based studies and osmphobia of migraineurs across population sample was not reported yet. The aims of this study are to assess osmophobia in migraineurs across Korean populationand to assess validity of alternative diagnostic criteria of migraine. Methods: We used data of Korean Headache Survey(KHS), a population-based study by a stratified random sampling in Korean population over age 19, and totally 1,507 were evaluated. Demographic profile, headache characteristics and impact of headache were assessed with a 12-item semi-structured interview. Headache type was identified according to ICHD-2. We assessed osmophobia by a question ‘Do you feel changes in your sense of smell during headache?(stronger or differently)’. Results: Prevalence for migraine was 6.1%. 50.5% of migraineurs reported osmophobia during migraine attack. Mig- raineurs with osmophobia had more headache aggravation by routine physical activity, phonophobia and higher HIT-6 score than migraineurs without osmophobia. There were no significant difference in unilaterality of pain, pain intensity in VAS score, pulsating quality and photophobia between migraineurs with osmophobia and migraineurs without osmo- phobia. The sensitivity of alternative criteria was 0.95[95% confidence interval(CI), 0.87-0.98] and specificity was 0.99(95% CI, 0.98-0.99). Conclusions: Approximately half of migraineurs across Korean population sample reported osmophobia. Alternative criteria showed good specificity and sensitivity.
- 보툴리눔 치료의 주사방법
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Kwang-Soo Lee, Yoon-Sang Oh
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Korean J Headache. 2011;12(1):27-30. Published online June 30, 2011
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- Chronic migraine is a prevalent and disabling neurological disorder. Preventive treatments are designed to reduce the fre- quency, severity, or duration of migraine attacks. Preventive agents include beta-adrenergic blockers, antidepressants, calcium channel antagonists, serotonin antagonists and anticonvulsants. Although daily oral prophylactic treatments have proven effective, issues such as lack of compliance with daily dosing regimens and adverse effects have limited their usefulness and resulted in a search for other modalities and agents, including botulinum neurotoxin. At 2010, the phase III research evaluating migraine prophylaxis therapy(PREEMPT) paradigm for injecting onabotulinumtoxin A has been shown to be safe, well tolerated, and effective in well designed, controlled clinical trials and was approved by USA, England and Korean FDA.
- 자가편두통 선별 도구의 개발 및 타당도 평가 -한국 편두통 선별 설문-
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Min-Kyung Chu, Byung Kun Kim, Sung Taek Kim, Jae-Moon Kim, Heui-Soo Moon, Jeong Wook Park, Kwang-Soo Lee, Kyung-Mi Oh, Jae-Myun Chung, Chin-Sang Chunge
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Korean J Headache. 2007;8(2):84-91. Published online December 31, 2007
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- Background
Migraine is a common and disabling illness. But substantial migraine sufferers were underdiagnosed or undiagnosed. To improve migraine diagnosis, Korean Migraine Screening Questionnaire(KMSQ) was developed and validated in outpatient setting. Methods: A total of 507 patients who visited out patient clinic for headache were recruited in 10 hospitals in Korea and asked 10-item questionnaire concerning headache. 487 completed and returned the questionnaire. All patients were evaluated for headache and diagnosed by headache experts. Migraine diagnosis was assigned on International Head- ache Society(IHS) criteria after completing semi-structured diagnostic interview. Results: Of ten diagnostic questions derived from IHS criteria and headache expert experience, three-item subsets were deduced. Combination of questions regarding nausea, pulsating quality and photophobia showed optimum perfor- mances. Any two from the three items showed a sensitivity of 0.74, a specificity of 0.80, a positive predictive value of 80.8 and a negative predictive value of 73.5. Conclusion: The three-item Korean Migraine Screening Questionnaire was a valid and reliable migraine screening instru- ment in outpatient setting. It could help in improvement of migraine diagnosis and enhance migraine management.
- 증례 : 말초 혈액의 호산구 증가 없이 발생한 호산구성 뇌막염
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Dong-Geun Lee, Joong-Seok Kim, In-Uk Song, Jeong-Wook Park, Kwang-Soo Lee
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Korean J Headache. 2006;7(2):112-114. Published online December 31, 2006
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- Eosinophilc meningitis is a rare clinical entity that can be useful in narrowing the differential diagnosis of central nervous system. The causes of eosinophilic meningitis are diverse: parasite infection, fungal infection, idiopathic hypereosinophilic syndrome, and Hodgkin's disease. But the most common cause of eosinophilic meningitis is invasion of the central nervous system by helminthic parasites, particularly Angiostrongylus cantonensis. And the most cases have occurred in Southeast Asia and throughout the Pacific basin, which are endemic areas. We report a patient with primary eosino- philic meningitis without eosinophilia.
- 증례 : 비행에 의해 유발되는 두통
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Young-Do Kim, In-Uk Song, Jeong-Wook Park, Joong-Seok Kim, Jae-Young An, Yeong-In Kim, Kwang-Soo Lee
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Korean J Headache. 2006;7(2):100-102. Published online December 31, 2006
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- A 46-year old man was admitted to neurology department because of severe headache associated only with airplane travel. When the plane started descending, a severe jabbing pain suddenly developed in the occipital area. The pain remained severe for 15 to 20 minutes until the plane landed. After the plane had landed, the pain alleviated spon- taneously and recovered completely after about 45 minutes. The brain computer tomography revealed chronic bilateral maxillary and right frontal sinusitis.
- 해면정맥동 이상이 선행하고 조직검사에서 확진된 톨로자헌트 증후군 1예
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Seon-Young Ryu, Sang-Bong Lee, Yeong-In Kim, Kwang-Soo Lee, Jeong-wook Park, Hye-Kyung Lee
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Korean J Headache. 2004;5(2):153-157. Published online December 31, 2004
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- Tolosa-Hunt syndrome(THS) is a painful ophthalmoplegia caused by an idiopathic granulomatous in- flammation of the superior orbital fissure or cavernous sinus of unknown etiology. A 72-year-old woman developed right-sided ophthalmoplegia with the pupillary dilatation and ptosis, and hypesthesia in the territory of the ophthalmic division of the right trigerminal nerve in May 2003. The MRI showed enlar- gement of right cavernous sinus by an enhancing soft tissue mass extending to the sellar region. Prior to this presentation, in August 2002, MRI done at another institusion already revealed the same soft tissue mass in the right cavernous sinus. The patient underwent a transsphenoidal biopsy which revealed chronic granulomatous inflammation with necrosis. The patient was treated with steroids, followed by the resolution of the neurologic symptoms. We report this case of biopsy-proven THS in which radiologic abnormality preceded clinical presentation by at least 10 months. Korean Journal of Headache 5(2):153-157, 2004
- 요통의 해부, 병인과 감별 진단
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Kwang-Soo Lee, Joong-Seok Kim
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Korean J Headache. 2001;2(2):111-112. Published online December 31, 2001
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- Physicians who work in primary care settings and neurology departments frequently evaluate patients with low back pain. However, there are wide variations in care, a fact that suggests there is professional uncertainty about optimal approach. In addition, there is evidence of excessive imaging and surgery for low back pain in Korea. In considering diagnostic tests, physicians should apply the principles outlined in an algorithm for the evaluation of low back pain, and must look for red flags- key historical and clinical clue that increase the likelihood of a serious underlying disorder. We discuss the epidemiology and etiology of back pain and review the literatures about diagnostic methods. Korean Journal of Headache 2(2):111-122, 2001
- 후천성면역결핍증 환자에서 보인 무세포성 크립토콕쿠스 뇌막염 2례
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Tae-Ho Guak, Joong-Seok Kim, Sung-Woo Chung, Kwang-Soo Lee
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Korean J Headache. 2001;2(1):64-77. Published online June 30, 2001
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- Cryptococcus meningitis is extraordinarily common in AIDS patients, with reported incidences varying between 1.9% and 11.0%. Cryptococcal meningitis in human immunodeficiency virus(HIV)-infected patients often results in relatively minor cerebrospinal fluid(CSF) changes, though in some cases, CSF profiles may be normal. We report here on the clinical manifestations of cryptococcal meningitis in AIDS patients without pleocytosis. As the number of patients with HIV infection increases in Korea, cryptococcal menin- gitis should be included in the differential diagnosis, if clinically warranted. Korean Journal of Headache 2(1):64-77, 2001
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